Senior/Principal Scientist-ADME

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: January 25, 2026

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Organization Overview: The Bioanalytical Research Group (BAR) at the Lilly Corporate Center, Indianapolis, IN is seeking a strong scientist skilled in molecular biology, immunoassays, and automated liquid handling to deliver innovative approaches for the quantitative assessment of biotherapeutic molecules. The team collaborates with toxicology, PK/PD, Biotechnology Discovery Research, and multiple biotherapeutic areas to help discover and characterize optimal biotherapeutic candidates to advance clinical testing, across a wide variety of modalities. Responsibilities: The primary responsibilities for this position include: The development, optimization, and execution of molecular biology and ligand binding assays to quantify biotherapeutic and new modality molecules in a wide variety of biological matrices. The development and implementation of liquid handling automation, including programming, streamline molecular biology and ligand binding assay formats. Documentation, interpretation, and communication of research results to internal leadership and therapeutic area program teams. Conduct laboratory research in a relatively independent fashion and with the flexibility to support a highly multifaceted portfolio. Basic Requirements: M.S. in biochemistry/molecular biology, bioengineering, biology, pharmacology, or pharmaceutical sciences with at least 1-year of experience working in a pharmaceutical research environment. Candidates with a B.S. in one of the above disciplines with 5 years of pharmaceutical research experience will be considered. Experience developing and utilizing immunoassays to study the ADME properties of biotherapeutic and new modality drugs. Experience using Tecan liquid handling automation to streamline molecular biology and immunoassay formats. Experience using Watson LIMS for analytical run creation and data analysis Experience planning, record keeping, and data analysis skills. Additional Skills/Preferences: Experience with Hybridization ELISA, qPCR, and tissue preparation techniques is highly desirable. Excellent written and verbal communication skills. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 - $193,600 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

Keywords: Eli Lilly and Company, Dayton , Senior/Principal Scientist-ADME, Science, Research & Development , Indianapolis, Ohio