Senior Director, Device Portfolio Insights

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: February 20, 2026

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Position Summary: The Senior Director of Device Portfolio Insights serves as enterprise owner of device portfolio strategy, investment prioritization, and long-range value creation. This role orchestrates cross-functional integration across R&D, Clinical, Therapeutic Areas, Commercial, Finance, and Digital to drive portfolio decisions that maximize strategic and financial return. This leader provides oversight of portfolio health, prioritization, and governance while ensuring integration between drug delivery devices and Lilly's clinical pipeline. Serving as the central hub for portfolio intelligence, this role drives resource allocation, investment optimization, and AI-enabled decision support. The position requires sophisticated analytical capabilities and the ability to synthesize complex information into actionable insights that guide executive decision-making. Responsibilities: Strategic Mandate and Enterprise Ownership Develop and maintain a comprehensive, integrated view of the device development portfolio spanning drug delivery pre-clinical & clinical research, device innovation, development, and commercialization projects, programs, and initiatives under device development Ensure seamless integration between drug delivery device development and Lilly's clinical molecule pipeline across all therapeutic areas Support annual portfolio strategic planning processes in collaboration with device development leadership Use market analysis, competitive intelligence, and technology assessments to inform portfolio strategy Identify whitespace opportunities and recommend new investment areas. Support build vs. buy vs. partner analyses for delivery system capabilities Cross?Functional Orchestration Leverage deep portfolio knowledge and financial expertise to optimize investment strategies at both project and portfolio levels Partner with Finance and PPM/CMC PM teams to develop accurate cost models, forecasts, and business cases for drug delivery system initiatives Track and report on portfolio expenditures, variance analysis, productivity, and return on investment metrics Support business case development for new initiatives and portfolio prioritization decisions Develop and update device development archetypes and support disease state benchmarking activities Decision-Focused Portfolio Intelligence Develop, maintain, and continuously enhance the device development portfolio dashboard to support data-driven decision-making Establish key performance indicators (KPIs) and metrics that provide meaningful insights into portfolio health, progress, and value realization Create visualizations and reporting tools that enable leadership to quickly assess portfolio status, risks, and opportunities Implement predictive analytics and modeling capabilities to forecast portfolio outcomes Artificial Intelligence and Decision Science Leadership Champion use of decision science, data science, and AI applications in device development business intelligence to improve portfolio operations Deploy predictive analytics and decision augmentation tools to enhance portfolio forecasting, risk assessment, scenario planning, and opportunity identification Identify resource constraints, bottlenecks, and capability gaps; recommend solutions Monitor resource utilization metrics and drive continuous improvement in capacity management Forward?Looking Portfolio Deployment Ensure clear and consistent communication of portfolio status, insights, and recommendations to device development leadership and cross-functional stakeholders Facilitate regular portfolio communication forums to share insights, trends, and priority shifts Identify, assess, and communicate portfolio-level risks, dependencies, and integration challenges. Develop risk mitigation strategies and contingency plans for high-impact portfolio risks Ensure transparent escalation of critical issues requiring leadership attention or intervention Build strong relationships with therapeutic area leaders, clinical development teams, and commercial stakeholders Translate complex portfolio data into compelling narratives for executive audiences Serve as Strategic Portfolio leader Prepare portfolio materials for governance reviews, decision forums, and executive leadership meetings Ensure governance readiness by maintaining current, accurate data on milestones, deliverables, risks, and dependencies Act as a trusted advisor to leadership on portfolio strategy and investment decisions Basic Requirements: Bachelor's degree in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with a minimum of 15 years of experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions Proven track record managing complex, multi-million-dollar portfolios with cross-functional dependencies Significant experience with drug delivery systems, medical devices, or combination products Demonstrated experience in resource management and capacity planning for R&D organizations Experience with pharmaceutical governance processes and investment decision-making Strong background in financial analysis, business case development, and investment optimization Additional Preferences: Advanced degree (MBA, MS, PhD) in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with a minimum of 10 years of progressive experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions Deep knowledge of portfolio management principles, frameworks, and best practices Experience with portfolio optimization methodologies and decision analysis techniques Proficiency with portfolio management tools and software (e.g., Planisware, Clarity, ServiceNow, Tableau) Understanding of stage-gate processes and governance frameworks in pharmaceutical R&D Knowledge of portfolio metrics, KPIs, and performance measurement systems Experience with agile portfolio management and adaptive planning approaches Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $156,000 - $228,800 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

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